Osteocalcin is a 49 amino acid protein, which is made by the bone forming osteoblasts. The protein contains three α-carboxylated glutamic acid residues (Gla), giving it a high affinity for calcium. It is also known as bone Gla protein and it is a major component of the non-collagenous bone matrix. Sixty to ninety percent of de novo synthesized osteocalcin is incorporated into the bone matrix, where it binds to hydroxy-apatite during matrix mineralization.
IDS Nordic a/s is committed to the development of diagnostic products for the improved management of patients suffering from bone and cartilage related diseases, such as osteoporosis, osteoarthritis, rheumatoid arthritis, and bone metastasis. We are among the world leaders in the niche field of bone and cartilage diagnostics and have a comprehensive research and development pipeline dedicated to these areas.
Osteocalcin What is Osteocalcin?
Osteocalcin is a 49 amino acid protein, which is made by the bone forming osteoblasts. The protein......
Bone markers IDS Nordic a/s promotes a panel of biochemical assays for assessment of bone diseases in in-vitro models, pre-clinical models and clinical studies.
Recently we joint partnerships with several biotech companies and suppliers. We act as their distributor for a wide range of biochemical assays and together with our own assays this enable us to provide a complete product range to our customers.
Read more about our bone marker assays that are divided into pre-clinical and clinical assays.
More information about bone markers
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Cartilage degradation Urine Pre-Clinical CartiLaps® ELISA
Cat. # 2CAL4000: Collagen type II is the major component of articular cartilage. Cartilage degradation of collagen fibers in articular cartilage is a critical and irreversible event in the pathology of arthritis. This fact, and the importance of collagen type II to the biomechanical properties of cartilage, suggests that collagen type II cartilage degradation is a key event in cartilage damage.
Serum Pre-Clinical CartiLaps® ELISA
Cat. # 3CAL4000: Collagen type II is the major component of articular cartilage. Cartilage degradation of collagen fibers in articular cartilage is a critical and irreversible event in the pathology of arthritis. This fact, and the importance of collagen type II to the biomechanical properties of cartilage, suggests that collagen type II degradation is a key event in cartilage damage.
Read more about the cartilage marker assays that are divided into pre-clinical and clinical assays:
Pre-clinical assaysClinical assays...
