Collagen type II

Biochemical markers of cartilage turnover

Cartilage is normally a tissue with a very slow metabolism, but in arthritic diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA) excess cartilage degradation is apparent. Clinical assessment of patients with RA and OA is performed by assessing the pain and mobility problems caused by the joint destruction and by X-ray or MRI assessments of the structural damage in the affected joint tissues. A number of standardised rating methods have been introduced for evaluation of pain and symptoms associated with joint diseases (i.e. HAQ, DAS, VAS and ACR scores), but it is difficult to quantify these parameters.

Read more about the cartilage assays that are divided into pre-clinical and clinical assays:

Pre-clinical assays
Clinical assays

IDS Nordic a/s is committed to the development of diagnostic products for the improved management of patients suffering from bone and cartilage related diseases, such as osteoporosis, osteoarthritis, rheumatoid arthritis, and bone metastasis. We are among the world leaders in the niche field of bone and cartilage diagnostics and have a comprehensive research and development pipeline dedicated to these areas.

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Collagen type II
Biochemical markers of cartilage turnover Cartilage is normally a tissue with a very slow metabolism, but in arthritic diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA) excess cartilage degradation is apparent. Clinical assessment of patients with RA and OA is performed by assessing the pain and mobility problems caused by the joint destruction and by X-ray or MRI assessments of the structural damage in the affected joint tissues. A number of standardised rating methods have been introduced for evaluation of pain and symptoms associated with joint diseases (i.e. HAQ, DAS, VAS and ACR scores), but it is difficult to quantify these parameters. Read more about the cartilage assays that are divided into pre-clinical and clinical assays: Pre-clinical assays Clinical assays...

Bone markers
IDS Nordic a/s promotes a panel of biochemical assays for assessment of bone diseases in in-vitro models, pre-clinical models and clinical studies. Recently we joint partnerships with several biotech companies and suppliers. We act as their distributor for a wide range of biochemical assays and together with our own assays this enable us to provide a complete product range to our customers. Read more about our bone marker assays that are divided into pre-clinical and clinical assays. More information about bone markers ...

Cartilage degradation
Urine Pre-Clinical CartiLaps® ELISA Cat. # 2CAL4000: Collagen type II is the major component of articular cartilage. Cartilage degradation of collagen fibers in articular cartilage is a critical and irreversible event in the pathology of arthritis. This fact, and the importance of collagen type II to the biomechanical properties of cartilage, suggests that collagen type II cartilage degradation is a key event in cartilage damage. Serum Pre-Clinical CartiLaps® ELISA Cat. # 3CAL4000: Collagen type II is the major component of articular cartilage. Cartilage degradation of collagen fibers in articular cartilage is a critical and irreversible event in the pathology of arthritis. This fact, and the importance of collagen type II to the biomechanical properties of cartilage, suggests that collagen type II degradation is a key event in cartilage damage. Read more about the cartilage marker assays that are divided into pre-clinical and clinical assays: Pre-clinical assays Clinical assays...