Bone turnover

Bone turnover is a dynamic process occurring at varying rates throughout the life cycle of an individual. The bone turnover process occurs to repair micro-fractures and other damage sustained by the skeleton. Furthermore, as the skeleton also serves as the body’s main calcium store, the process serves to regulate calcium concentrations within the narrow range necessary to maintain essential bodily functions. Bone turnover comprises formation and resorption, which are two distinct but coupled processes (see figure). The processes of bone formation mediated by cells of the osteoblastic lineage and bone resorption mediated by osteoclasts are usually tightly coupled and highly regulated.

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IDS Nordic a/s is committed to the development of diagnostic products for the improved management of patients suffering from bone and cartilage related diseases, such as osteoporosis, osteoarthritis, rheumatoid arthritis, and bone metastasis. We are among the world leaders in the niche field of bone and cartilage diagnostics and have a comprehensive research and development pipeline dedicated to these areas.

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Bone turnover
Bone turnover is a dynamic process occurring at varying rates throughout the life cycle of an individual. The bone turnover process occurs to repair micro-fractures and other damage sustained by the skeleton. Furthermore, as the skeleton also serves as the body’s main calcium store, the process serves to regulate calcium concentrations within the narrow range necessary to maintain essential bodily functions. Bone turnover comprises formation and resorption, which are two distinct but coupled processes (see figure). The processes of bone formation mediated by cells of the osteoblastic lineage and bone resorption mediated by osteoclasts are usually tightly coupled and highly regulated. More information about bone turnover......

Bone markers
IDS Nordic a/s promotes a panel of biochemical assays for assessment of bone diseases in in-vitro models, pre-clinical models and clinical studies. Recently we joint partnerships with several biotech companies and suppliers. We act as their distributor for a wide range of biochemical assays and together with our own assays this enable us to provide a complete product range to our customers. Read more about our bone marker assays that are divided into pre-clinical and clinical assays. More information about bone markers ...

Cartilage degradation
Urine Pre-Clinical CartiLaps® ELISA Cat. # 2CAL4000: Collagen type II is the major component of articular cartilage. Cartilage degradation of collagen fibers in articular cartilage is a critical and irreversible event in the pathology of arthritis. This fact, and the importance of collagen type II to the biomechanical properties of cartilage, suggests that collagen type II cartilage degradation is a key event in cartilage damage. Serum Pre-Clinical CartiLaps® ELISA Cat. # 3CAL4000: Collagen type II is the major component of articular cartilage. Cartilage degradation of collagen fibers in articular cartilage is a critical and irreversible event in the pathology of arthritis. This fact, and the importance of collagen type II to the biomechanical properties of cartilage, suggests that collagen type II degradation is a key event in cartilage damage. Read more about the cartilage marker assays that are divided into pre-clinical and clinical assays: Pre-clinical assays Clinical assays...